Do you have any ideas or suggestions about information that you would find helpful to see on this website, please contact one of our Project Leaders:

Marie-Hélène Masse
Julie Ménard
Sheila Sprague

Thanks to all Participating Centers and collaborators for engaging in this research program!

Thanks to the CCCTG for endorsing this research project.


Lessening Organ Dysfunction with VITamin C

The LOVIT Trial is a multicentre concealed-allocation parallel-group blinded randomized controlled trial to ascertain the effect of high-dose intravenous vitamin C compared to placebo on mortality or persistent organ dysfunction at 28 days in septic intensive care unit patients.
The principal investigators of the LOVIT Trial are Dr. François Lamontagne and Dr. Neill Adhikari.

This study will be centrally coordinated by the Unité de Recherche Clinique et Épidémiologique (URCE) at the Research Center of the Centre Hospitalier Universitaire de Sherbrooke (CRCHUS), Sherbrooke, QC, Canada. 

This trial will be conducted in 25 sites in Canada. Additional clinical sites will be included as needed.

CONTACT US if you are interested in joining this trial.